Plenary 3.2

9/1 8:00 - 10:30, Memorial Auditorium

Toward a Whole-Cell Model of Mycoplasma genitalium

Markus W. Covert

Assistant Professor of Bioengineering, Stanford University.

Markus W. CovertOur focus is on building computational models of complex biological processes, and using these models to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-κB, an important family of transcription factors whose aberrant activity has been linked to oncogenesis, tumor progression, and resistance to chemotherapy.