Plenary Session 6 – Dynamics

9/2 4:00 - 6:00, Memorial Auditorium

Plenary Session 6.1

Michael B. Elowitz

California Institute of Technology.

Plenary Session 6.2

Evolutionary Dynamics and Biological Disorganization

Daniel S. Fisher

Stanford University.

Plenary Session 6.3

Protein localization is important for bacterial cell-cycle regulation?

Kerwyn C. Huang

Stanford University.

In this talk, I will describe how pole-to-pole oscillations of the Min-protein system help to regulate cell division in E. coli. We have developed a model of the Min system which accurately reproduces the observed oscillations in rod-shaped, round, and branched cells. These results suggest that oscillations may provide a general mechanism by which proteins can localize in response to features of cell geometry. As a counterpoint to the importance of spatial localization in the Min system, I will also present evidence that misclocalization of the cell-cycle control system in Caulobacter crescentus can be corrected for by overexpression, suggesting that localization may have evolved via selection for efficiency.

Plenary Session 6.4

Alexander van Oudenaarden

Massachusetts Institute of Technology.